"BAG3" Related Products

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Recombinant Human BAG3 Protein, MYC/DDK-tagged

Cat.No. : BAG3-2138H
Product Overview : Recombinant human BAG3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description : BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 61.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : BAG3 BCL2-associated athanogene 3 [ Homo sapiens ]
Official Symbol : BAG3
Synonyms : BAG-3; BIS; CAIR-1; MFM6
Gene ID : 9531
mRNA Refseq : NM_004281
Protein Refseq : NP_004272
MIM : 603883
UniProt ID : O95817

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