Recombinant Human BCAS2 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: BCAS2-414H
• Product Overview: BCAS2 MS Standard C13 and N15-labeled recombinant protein (NP_005863) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). [UniProtKB/Swiss-Prot Function]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.1 kDa
• AA Sequence: MAGTGLVAGEVVVDALPYFDQGYEA PGVREAAAALVEEETRRYRPTKNYL SYLTAPDYSAFETDIMRNEFERLAA RQPIELLSMKRYELPAPSSGQKNDI TAWQECVNNSMAQLEHQAVRIENLE LMSQHGCNAWKVYNENLVHMIEHAQ KELQKLRKHIQDLNWQRKNMQLTAG SKLREMESNWVSLVSKNYEIERTIV QLENEIYQIKQQHGEANKENIRQDF TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BCAS2 breast carcinoma amplified sequence 2 [ Homo sapiens (human) ]
• Official Symbol: BCAS2
• Synonyms: BCAS2; breast carcinoma amplified sequence 2; pre-mRNA-splicing factor SPF27; DAM1; Snt309; SPF27; breast carcinoma-amplified sequence 2; spliceosome-associated protein SPF 27; DNA amplified in mammary carcinoma 1 protein; spliceosome associated protein, amplified in breast cancer
• Gene ID: 10286
• mRNA Refseq: NM_005872
• Protein Refseq: NP_005863
• MIM: 605783
• UniProt ID: O75934