| Description : |
Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
99.5 kDa |
| AA Sequence : |
MNEAMATDSPRRPSRCTGGVVVRPQ AVTEQSYMESVVTFLQDVVPQAYSG TPLTEEKEKIVWVRFENADLNDTSR NLEFHEIHSTGSEPPLLIMIGYSDG MQVWSIPISGEAQELFSVRHGPIRA ARILPAPQFGAQKCDNFAEKRPLLG VCKSIGSSGTSPPYCCVDLYSLRTG EMVKSIQFKTPIYDLHCNKRILVVV LQEKIAAFDSCTFTKKFFVTSCYPC PGPNMNPIALGSRWLAYAENKLIRC HQSRGGACGDNIQSYTATVISAAKT LKSGLTMVGKVVTQLTGTLPSGVTE DDVAIHSNSRRSPLVPGIITVIDTE TVGEGQVLVSEDSDSDGIVAHFPAH EKPVCCMAFNTSGMLLVTTDTLGHD FHVFQILTHPWSSSQCAVHHLYTLH RGETEAKVQDICFSHDCRWVVVSTL RGTSHVFPINPYGGQPCVRTHMSPR VVNRMSRFQKSAGLEEIEQELTSKQ GGRCSPVPGLSSSPSGSPLHGKLNS QDSYNNFTNNNPGNPRLSPLPSLMV VMPLAQIKQPMTLGTITKRTGKVKP PPQISPSKSMGGEFCVAAIFGTSRS WFANNAGLKREKDQSKQVVVESLYI ISCYGTLVEHMMEPRPLSTAPKISD DTPLEMMTSPRASWTLVRTPQWNEL QPPFNANHPLLLAADAVQYYQFLLA GLVPPGSPGPITRHGSYDSLASDHS GQEDEEWLSQVEIVTHTGPHRRLWM GPQFQFKTIHPSGQTTVISSSSSVL QSHGPSDTPQPLLDFDTDDLDLNSL RIQPVRSDPVSMPGSSRPVSDRRGV STVIDAASGTFDRSVTLLEVCGSWP EGFGLRHMSSMEHTEEGLRERLADA MAESPSRDVVGSGTELQREGSIETL SNSSGSTSGSIPRNFDGYRSPLPTN ESQPLSLFPTGFPTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
