Recombinant Human BCCIP Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | BCCIP-4365H |
Product Overview : | BCCIP MS Standard C13 and N15-labeled recombinant protein (NP_510868) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 36.1 kDa |
AA Sequence : | MASRSKRRAVESGVPQPPDPPVQRD EEEEKEVENEDEDDDDSDKEKDEED EVIDEEVNIEFEAYSLSDNDYDGIK KLLQQLFLKAPVNTAELTDLLIQQN HIGSVIKQTDVSEDSNDDMDEDEVF GFISLLNLTERKGTQCVEQIQELVL RFCEKNCEKSMVEQLDKFLNDTTKP VGLLLSERFINVPPQIALPMYQQLQ KELAGAHRTNKPCGKCYFYLLISKT FVEAEKNNSKKKPSNKKKAALMFAN AEEEFFYEKAILKFNYSVQEESDTC LGGKWSFDDVPMTPLRTVMLIPGDK MNEIMDKLKEYLSVTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | BCCIP BRCA2 and CDKN1A interacting protein [ Homo sapiens (human) ] |
Official Symbol : | BCCIP |
Synonyms : | BCCIP; BRCA2 and CDKN1A interacting protein; BRCA2 and CDKN1A-interacting protein; BCCIPalpha; TOK 1; BCCIPbeta; TOK-1beta; TOK-1alpha; protein TOK-1; cdk inhibitor p21 binding protein; p21- and CDK-associated protein 1; BRCA2 and Cip1/p21 interacting protein; TOK1; TOK-1; |
Gene ID : | 56647 |
mRNA Refseq : | NM_078468 |
Protein Refseq : | NP_510868 |
MIM : | 611883 |
UniProt ID : | Q9P287 |
Products Types
◆ Recombinant Protein | ||
Bccip-1845M | Recombinant Mouse Bccip Protein, Myc/DDK-tagged | +Inquiry |
BCCIP-347R | Recombinant Rhesus Macaque BCCIP Protein, His (Fc)-Avi-tagged | +Inquiry |
BCCIP-2365H | Recombinant Human BCCIP Protein, MYC/DDK-tagged | +Inquiry |
BCCIP-982M | Recombinant Mouse BCCIP Protein, His (Fc)-Avi-tagged | +Inquiry |
BCCIP-434H | Recombinant Human BCCIP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BCCIP-001HCL | Recombinant Human BCCIP cell lysate | +Inquiry |
BCCIP-002HCL | Recombinant Human BCCIP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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