Recombinant Human BCL2 Binding Component 3, His-tagged

• Cat.No.: BBC3-1561H
• Product Overview: Recombinant Human BBC3 was expressed inE.Coliusing an N-terminal His tag. MW= 15 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse.
• Sequence: 6-170.
• Purity: ~95%.
• Specific Activity: n/aH.
• Applications: E, WB, MS.
• Buffer: 1X PBS containing 0.1% SDS and 0.02% NaN3
• Storage: Store at -70?C. As with any protein, exposing BBC3 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• SDS-PAGE: SDS PAGE Analysis of BBC3 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.

Gene Information

• Gene Name: BBC3 BCL2 binding component 3 [ Homo sapiens ]
• Synonyms: BBC3; BCL2 binding component 3; JFY1; PUMA; FLJ42994; p53 up-regulated modulator of apoptosis
• Gene ID: 27113
• mRNA Refseq: NM_001127240
• Protein Refseq: NP_001120712
• MIM: 605854
• UniProt ID: Q9BXH1
• Chromosome Location: 19q13.3-q13.4
• Pathway: Huntington"s disease; p53 signaling pathway; Apoptosis
• Function: protein binding