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Recombinant Human BCL2L1 Protein

Cat.No. : BCL2L1-168H
Product Overview : Recombinant Human BCL2L1, transcript variant 2, was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Source : E. coli
Species : Human
Form : 20mM HEPES, 50mM KCl, 20% Glycerol, pH 7.5.
Molecular Mass : 24.8 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Storage : Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : BCL2L1 BCL2-like 1 [ Homo sapiens ]
Official Symbol : BCL2L1
Synonyms : BCL2L1; BCL2-like 1; bcl-2-like protein 1; Bcl X; bcl xL; bcl xS; BCL2L; BCLX; PPP1R52; protein phosphatase 1; regulatory subunit 52; apoptosis regulator Bcl-X; protein phosphatase 1, regulatory subunit 52; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; BCL-XL/S; DKFZp781P2092;
Gene ID : 598
mRNA Refseq : NM_001191
Protein Refseq : NP_001182
MIM : 600039
UniProt ID : Q07817

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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