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Recombinant Human BCL6 protein, His-tagged

Cat.No. : BCL6-1362H
Product Overview : Recombinant Human BCL6 protein(P41182)(1-706aa), fused to N-terminal His tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : His
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 84.8 kDa
Protein length : 1-706aa
Purity : Greater than 90% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : BCL6 B-cell CLL/lymphoma 6 [ Homo sapiens ]
Official Symbol : BCL6
Synonyms : BCL6; B-cell CLL/lymphoma 6; zinc finger protein 51 , ZNF51; B-cell lymphoma 6 protein; BCL5; BCL6A; LAZ3; ZBTB27; BCL-5; BCL-6; protein LAZ-3; zinc finger protein 51; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein transcript; zinc finger transcription factor BCL6S; cys-his2 zinc finger transcription factor; zinc finger and BTB domain-containing protein 27; lymphoma-associated zinc finger gene on chromosome 3; ZNF51;
Gene ID : 604
mRNA Refseq : NM_001130845
Protein Refseq : NP_001124317
MIM : 109565
UniProt ID : P41182

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
04/21/2022

    Its stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.

    09/22/2021

      I am delighted to highly recommend the BCL6 Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis

      12/11/2016

        Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.

        Q&As (5)

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        What are the current challenges in targeting BCL6 protein for therapeutic purposes? 02/21/2023

        Challenges include the need to develop specific and effective inhibitors of BCL6 function while minimizing off-target effects and ensuring tolerability in clinical settings.

        Are there any known genetic mutations or alterations in the BCL6 gene associated with disease susceptibility? 10/07/2022

        Yes, genetic mutations and translocations involving the BCL6 gene have been linked to the development of certain lymphomas and other hematological malignancies.

        What role does BCL6 protein play in the germinal center reaction? 06/13/2022

        BCL6 protein is crucial for the formation and maintenance of germinal centers, where it regulates the processes of somatic hypermutation and class-switch recombination in B cells.

        How might targeting BCL6 protein offer new therapeutic options for autoimmune diseases? 06/30/2021

        Targeting BCL6 protein could potentially offer new therapeutic options by modulating immune responses and suppressing the aberrant production of autoantibodies in autoimmune diseases.

        Can the assessment of BCL6 protein expression aid in the prognosis of lymphoma patients? 05/22/2017

        Yes, the assessment of BCL6 protein expression can provide valuable prognostic information, helping to predict patient outcomes and guide treatment strategies for lymphoma patients.

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