Recombinant Human BDKRB2 Protein, His&GST-tagged

• Cat.No.: BDKRB2-309H
• Product Overview: Recombinant Human BDKRB2 Protein (Met1-Gln391) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 74.5 kDa
  Accurate Molecular Mass: 75 kDa
• Protein length: Met1-Gln391
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: BDKRB2 bradykinin receptor B2 [ Homo sapiens (human) ]
• Official Symbol: BDKRB2
• Synonyms: BDKRB2; bradykinin receptor B2; B2 bradykinin receptor; BK 2; BK-2 receptor; B2R; BK2; BK-2; BKR2; BRB2; DKFZp686O088
• Gene ID: 624
• mRNA Refseq: NM_000623
• Protein Refseq: NP_000614
• MIM: 113503
• UniProt ID: P30411