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Recombinant Human BDNF Protein, MYC/DDK-tagged

Cat.No. : BDNF-2466H
Product Overview : Recombinant Human BDNF protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 25.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : BDNF brain-derived neurotrophic factor [ Homo sapiens ]
Official Symbol : BDNF
Synonyms : ANON2; BULN2
Gene ID : 627
mRNA Refseq : NM_001143805
Protein Refseq : NP_001137277
MIM : 113505
UniProt ID : P23560

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is BDNF measured in clinical settings? 10/26/2021

BDNF levels can be measured through blood tests or cerebrospinal fluid analysis, providing insights into the protein's concentration in the body.

What neurological disorders are associated with BDNF deficiency? 10/03/2018

BDNF deficiency has been linked to conditions such as Alzheimer's disease, Parkinson's disease, and depression.

Are there medications that target BDNF for clinical use? 08/02/2018

While there are no direct BDNF medications, certain drugs and treatments aim to enhance BDNF levels indirectly, offering potential therapeutic benefits.

How does physical exercise influence BDNF levels, and what implications does this have for clinical applications? 06/24/2017

Physical exercise has been shown to increase BDNF production, suggesting that exercise could be used as a non-pharmacological intervention to support neurological health.

What role does BDNF play in synaptic plasticity, and how does it impact learning and memory? 01/28/2016

BDNF is crucial for synaptic plasticity, influencing the strength and efficacy of connections between neurons, which is vital for learning and memory processes.

Customer Reviews (3)

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12/31/2022

    The BDNF protein is carefully characterized, and its functional properties are well-documented.

    04/08/2021

      With its high purity and bioactivity, BDNF protein ensures reliable and consistent results in a wide range of experimental applications.

      11/27/2017

        The BDNF protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.

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