Recombinant Human BECN1 protein, His/MBP-tagged
Cat.No. : | BECN1-295H |
Product Overview : | Recombinant Human BECN1(127-268 aa) fused with His/MBP tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His/MBP |
Form : | Liquid in PBS |
Protein length : | 127-268 aa |
Purity : | SDS-PAGE >90% |
Applications : | WB Positive Control |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | BECN1 beclin 1, autophagy related [ Homo sapiens ] |
Official Symbol : | BECN1 |
Synonyms : | BECN1; beclin 1, autophagy related; beclin 1 (coiled coil, moesin like BCL2 interacting protein); beclin-1; ATG6; ATG6 autophagy related 6 homolog (S. cerevisiae); VPS30; ATG6 autophagy related 6 homolog; coiled-coil myosin-like BCL2-interacting protein; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin1; |
Gene ID : | 8678 |
mRNA Refseq : | NM_003766 |
Protein Refseq : | NP_003757 |
MIM : | 604378 |
UniProt ID : | Q14457 |
Products Types
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionBECN1 is involved in cancer, influencing both tumor suppression and survival.
It helps maintain cellular health by regulating the degradation and recycling of cellular components.
BECN1, a key autophagy protein, initiates the autophagic process, crucial for cellular waste disposal.
BECN1 interacts with a network of autophagy proteins, coordinating the autophagic response.
Altered BECN1 activity is linked to neurodegeneration, as autophagy is essential for neuronal health.
Targeting BECN1 could provide new treatments for cancer and neurodegenerative diseases by modulating autophagy.
Genetic mutations in BECN1 can lead to dysfunctional autophagy, affecting cell survival and health.
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