Recombinant Human BEST4, His-tagged

• Cat.No.: BEST4-10210H
• Product Overview: Recombinant Human BEST4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 95-473a.a.
• Description: This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3 ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: BEST4 bestrophin 4 [ Homo sapiens ]
• Official Symbol: BEST4
• Synonyms: BEST4; bestrophin 4; vitelliform macular dystrophy 2 like 2 , VMD2L2; bestrophin-4; vitelliform macular dystrophy 2-like 2; vitelliform macular dystrophy 2-like protein 2; VMD2L2; MGC126872
• Gene ID: 266675
• mRNA Refseq: NM_153274
• Protein Refseq: NP_695006
• MIM: 607336
• UniProt ID: Q8NFU0
• Chromosome Location: 1p33-p32.3
• Function: chloride channel activity; ion channel activity; molecular_function