"BIRC2" Related Products

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Recombinant Human BIRC2 protein, His/GST-tagged

Cat.No.: BIRC2-5894H
Product Overview: Recombinant Human BIRC2(1-221aa) fused with His/GST tag was expressed in E. coli.
Description: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis.
Source: E. coli
Species: Human
Tag: His/GST
Form: Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
Molecular Mass: 60.2 kDa
Purity: Greater than 95%
Storage: Store at +4 centigrade for up to 1 month, or aliquot and store at -80 centigrade for up to 12 months. Avoid repeat freeze-thaw cycles.
Gene Name: BIRC2 baculoviral IAP repeat containing 2 [ Homo sapiens ]
Official Symbol: BIRC2
Synonyms: BIRC2; baculoviral IAP repeat containing 2; API1, baculoviral IAP repeat containing 2; baculoviral IAP repeat-containing protein 2; apoptosis inhibitor 1; c IAP1; cIAP1; hiap 2; MIHB; NFR2 TRAF signalling complex protein; RNF48; IAP-2; IAP homolog B; RING finger protein 48; inhibitor of apoptosis protein 2; baculoviral IAP repeat-containing 2; NFR2-TRAF signalling complex protein; TNFR2-TRAF-signaling complex protein 2; API1; HIAP2; Hiap-2; c-IAP1;
Gene ID: 329
mRNA Refseq: NM_001166
Protein Refseq: NP_001157
MIM: 601712
UniProt ID: Q13490
Chromosome Location: 11q22
Pathway: Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem;
Function: metal ion binding; protein N-terminus binding; protein binding; transcription coactivator activity; ubiquitin-protein ligase activity; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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