Recombinant Human BMPR1A protein, hIgG/His-tagged

Cat.No.: BMPR1A-142H
Product Overview: Recombinant Human BMPR1A(24-152aa) fused with hIgG/His tag at N-terminal was expressed in Insect cells.
Description: BMPR1A, also known as bone morphogenetic protein receptor type-1A, is secreted cytokines/growth factors belonging to the Transforming Growth Factor beta (TGFbeta) family. It has been shown to be overexpressed in human breast cancers. Its deletion impairs mammary tumor formation and metastasis. It plays important roles in the differentiation and development of neurons. Its expression is up-regulated during bone formation, and that they may play important roles in bone morphogenesis. Recombinant human BMPR1A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Source: Insect cells
Species: Human
Tag : hIgG/His
Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass: 41.4kDa (371aa)
40-57kDa (SDS-PAGE under reducing conditions)
AA Sequence: ADPQNLDSML HGTGMKSDSD QKKSENGVTL APEDTLPFLK CYCSGHCPDD AINNTCITNG HCFAIIEEDD QGETTLASGC MKYEGSDFQC
KDSPKAQLRR TIECCRTNLC NQYLQPTLPP VVIGPFFDGS IRLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV
VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP
PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS
LSPGKHHHHH H
Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity: > 95% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Absorbance at 280nm)
Gene Name: BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Official Symbol: BMPR1A
Synonyms: BMPR1A; bone morphogenetic protein receptor, type IA; ACVRLK3; bone morphogenetic protein receptor type-1A; ALK3; CD292; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-protein kinase receptor R5; SKR5; 10q23del;
Gene ID: 657
mRNA Refseq: NM_004329
Protein Refseq: NP_004320
MIM: 601299
UniProt ID: P36894
Chromosome Location: 10q22.3
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Heart Development, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem;
Function: ATP binding; SMAD binding; activin receptor activity, type II; metal ion binding; nucleotide binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity; receptor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.