Recombinant Human BMPR1A Protein, MYC/DDK-tagged BMPR1A-2706H

Recombinant Human BMPR1A Protein, MYC/DDK-tagged

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Recombinant Human BMPR1A Protein, MYC/DDK-tagged

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Cat.No. : BMPR1A-2706H
Product Overview : Recombinant Human BMPR1A protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 57.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Official Symbol : BMPR1A
Synonyms : 10q23del; ACVRLK3; ALK3; CD292; SKR5
Gene ID : 657
mRNA Refseq : NM_004329
Protein Refseq : NP_004320
MIM : 601299
UniProt ID : P36894

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