Recombinant Human BOLL, GST-tagged

• Cat.No.: BOLL-10269H
• Product Overview: Recombinant Human BOLL protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-283a.a.
• Description: This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: BOLL bol, boule-like (Drosophila) [ Homo sapiens ]
• Official Symbol: BOLL
• Synonyms: BOLL; bol, boule-like (Drosophila); bol (Drosophila boule homolog) like; protein boule-like; BOULE
• Gene ID: 66037
• mRNA Refseq: NM_033030
• Protein Refseq: NP_149019
• MIM: 606165
• UniProt ID: Q8N9W6
• Chromosome Location: 2q33
• Function: RNA binding; nucleotide binding; protein binding; translation activator activity