Recombinant Human BPGM Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human BPGM Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : BPGM-3728H
Product Overview : BPGM MS Standard C13 and N15-labeled recombinant protein (NP_001715) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 30 kDa
AA Sequence : MSKYKLIMLR HGEGAWNKEN RFCSWVDQKL NSEGMEEARN CGKQLKALNF EFDLVFTSVL NRSIHTAWLI LEELGQEWVP VESSWRLNER HYGALIGLNR EQMALNHGEE QVRLWRRSYN VTPPPIEESH PYYQEIYNDR RYKVCDVPLD QLPRSESLKD VLERLLPYWN ERIAPEVLRG KTILISAHGN SSRALLKHLE GISDEDIINI TLPTGVPILL ELDENLRAVG PHQFLGDQEA IQAAIKKVED QGKVKQAKKT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BPGM 2,3-bisphosphoglycerate mutase [ Homo sapiens (human) ]
Official Symbol : BPGM
Synonyms : BPGM; 2,3-bisphosphoglycerate mutase; bisphosphoglycerate mutase; BPG-dependent PGAM; 2,3-diphosphoglycerate mutase; 2,3-bisphosphoglycerate synthase; erythrocyte 2,3-bisphosphoglycerate mutase; 2,3-bisphosphoglycerate mutase, erythrocyte; DPGM;
Gene ID : 669
mRNA Refseq : NM_001724
Protein Refseq : NP_001715
MIM : 613896
UniProt ID : P07738

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