| Gene Name |
BRCA1 breast cancer 1, early onset [ Homo sapiens ] |
| Official Symbol |
BRCA1 |
| Synonyms |
BRCA1; breast cancer 1, early onset; breast cancer type 1 susceptibility protein; BRCA1/BRCA2 containing complex; subunit 1; BRCC1; PPP1R53; protein phosphatase 1; regulatory subunit 53; RNF53; RING finger protein 53; BRCA1/BRCA2-containing complex, subunit 1; protein phosphatase 1, regulatory subunit 53; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; IRIS; PSCP; BRCAI; PNCA4; BROVCA1; |
| Gene ID |
672 |
| mRNA Refseq |
NM_007294 |
| Protein Refseq |
NP_009225 |
| MIM |
113705 |
| UniProt ID |
P38398 |
| Chromosome Location |
17q21-q24 |
| Pathway |
ATF-2 transcription factor network, organism-specific biosystem; ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; |
| Function |
DNA binding; DNA binding; RNA binding; androgen receptor binding; damaged DNA binding; enzyme binding; ligase activity; metal ion binding; protein binding; transcription coactivator activity; transcription regulatory region DNA binding; tubulin binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; contributes_to ubiquitin-protein ligase activity; zinc ion binding; |
