Recombinant Human BRINP3 protein, His & T7-tagged

• Cat.No.: BRINP3-1569H
• Product Overview: Recombinant Human BRINP3 aa. (Arg74~Ala264 (Accession # Q76B58)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Arg74~Ala264
• Description: This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.4kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 9.7

Gene Information

• Gene Name: BRINP3 BMP/retinoic acid inducible neural specific 3 [ Homo sapiens (human) ]
• Official Symbol: BRINP3
• Synonyms: BRINP3; BMP/retinoic acid inducible neural specific 3; FAM5C; DBCCR1L; DBCCR1L1; BMP/retinoic acid-inducible neural-specific protein 3; DBCCR1-like protein 1; bone morphogenetic protein/retinoic acid inducible neural-specific 3; family with sequence similarity 5, member C; protein FAM5C
• Gene ID: 339479
• mRNA Refseq: NM_001317188.1
• Protein Refseq: NP_001304117.1
• UniProt ID: Q76B58