Recombinant Human BRMS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human BRMS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : BRMS1-1591H
Product Overview : BRMS1 MS Standard C13 and N15-labeled recombinant protein (NP_056214) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 28.5 kDa
AA Sequence : MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAAVSPQK RKSDGPTRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BRMS1 breast cancer metastasis suppressor 1 [ Homo sapiens (human) ]
Official Symbol : BRMS1
Synonyms : BRMS1; breast cancer metastasis suppressor 1; breast cancer metastasis-suppressor 1; DKFZP564A063; DKFZp564A063;
Gene ID : 25855
mRNA Refseq : NM_015399
Protein Refseq : NP_056214
MIM : 606259
UniProt ID : Q9HCU9

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