Recombinant Human CACNB1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CACNB1-6188H
• Product Overview: CACNB1 MS Standard C13 and N15-labeled recombinant protein (NP_000714) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 65.5 kDa
• AA Sequence: MVQKTSMSRGPYPPSQEIPMEVFDP SPQGKYSKRKGRFKRSDGSTSSDTT SNSFVRQGSAESYTSRPSDSDVSLE EDREALRKEAERQALAQLEKAKTKP VAFAVRTNVGYNPSPGDEVPVQGVA ITFEPKDFLHIKEKYNNDWWIGRLV KEGCEVGFIPSPVKLDSLRLLQEQK LRQNRLGSSKSGDNSSSSLGDVVTG TRRPTPPASAKQKQKSTEHVPPYDV VPSMRPIILVGPSLKGYEVTDMMQK ALFDFLKHRFDGRTSITRVTADISL AKRSVLNNPSKHIIIERSNTRSSLA EVQSEIERIFELARTLQLVALDADT INHPAQLSKTSLAPIIVYIKITSPK VLQRLIKSRGKSQSKHLNVQIAASE KLAQCHPEMFDIILDENQLEDACEH LAEYLEAYWKATHPPSSTPPNPLLN RTMATAALAASPAPVSNLQGPYLAS GDQPLERATGEHASMHEYPGELGQP PGLYPSSHPPGRAGTLRALSRQDTF DADTPGSRNSAYTELGDSCVDMETD PSEGPGLGDPAGGGTPPARQGSWED EEEDYEEELTDNRNRGRNKARYCAE GGGPVLGRNKNELEGWGRGVYIRTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 [ Homo sapiens (human) ]
• Official Symbol: CACNB1
• Synonyms: CACNB1; calcium channel, voltage-dependent, beta 1 subunit; CACNLB1; voltage-dependent L-type calcium channel subunit beta-1; calcium channel, L type, beta 1 polypeptide; calcium channel voltage-dependent subunit beta 1; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; CAB1; CCHLB1; MGC41896
• Gene ID: 782
• mRNA Refseq: NM_000723
• Protein Refseq: NP_000714
• MIM: 114207
• UniProt ID: Q02641