Recombinant Human CACNB4 Protein, GST-Tagged
Cat.No. : | CACNB4-0274H |
Product Overview : | Human CACNB4 full-length ORF (NP_000717.2, 1 a.a. - 520 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 84.6 kDa |
AA Sequence : | MSSSSYAKNGTADGPHSPTSQVARG TTTRRSRLKRSDGSTTSTSFILRQG SADSYTSRPSDSDVSLEEDREAIRQ EREQQAAIQLERAKSKPVAFAVKTN VSYCGALDEDVPVPSTAISFDAKDF LHIKEKYNNDWWIGRLVKEGCEIGF IPSPLRLENIRIQQEQKRGRFHGGK SSGNSSSSLGEMVSGTFRATPTSTA KQKQKVTEHIPPYDVVPSMRPVVLV GPSLKGYEVTDMMQKALFDFLKHRF DGRISITRVTADISLAKRSVLNNPS KRAIIERSNTRSSLAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKT SLAPIIVHVKVSSPKVLQRLIKSRG KSQSKHLNVQLVAADKLAQCPPEMF DVILDENQLEDACEHLGEYLEAYWR ATHTTSSTPMTPLLGRNLGSTALSP YPTAISGLQSQRMRHSNHSTENSPI ERRSLMTSDENYHNERARKSRNRLS SSSQHSRDHYPLVEEDYPDSYQDTY KPHRNRGSPGGYSHDSRHRL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CACNB4 calcium channel,voltage-dependent,beta 4 subunit [ Homo sapiens ] |
Official Symbol : | CACNB4 |
Synonyms : | CACNB4;Cavβ4 Calcium Channel;EA5;EJM;calcium channel,voltage-dependent,beta 4 subunit;CAB4;EIG9;EJM4;EJM6;CACNLB4;voltage-dependent L-type calcium channel subunit beta-4;calcium channel voltage-dependent subunit beta 4;dihydropyridine-sensitive L-type,cal |
Gene ID : | 785 |
mRNA Refseq : | NM_000726 |
Protein Refseq : | NP_000717 |
MIM : | 601949 |
UniProt ID : | O00305 |
Products Types
◆ Recombinant Protein | ||
Cacnb4-738M | Recombinant Mouse Cacnb4 Protein, MYC/DDK-tagged | +Inquiry |
CACNB4-056H | Recombinant Human CACNB4 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CACNB4-431R | Recombinant Rhesus Macaque CACNB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CACNB4-603R | Recombinant Rhesus monkey CACNB4 Protein, His-tagged | +Inquiry |
CACNB4-10640H | Recombinant Human CACNB4, His-tagged | +Inquiry |
◆ Lysates | ||
CACNB4-7902HCL | Recombinant Human CACNB4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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