Active Recombinant Human CAMK2G Protein, GST-Tagged

• Cat.No.: CAMK2G-0334H
• Product Overview: Human CAMK2G (NP_751910.1, 1 a.a. - 518 a.a.) full-length recombinant protein with GST tag expressed in baculovirus infected Sf21 cells. cells.

Specification

• Description: The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]
• Source: Insect Cell
• Species: Human
• Tag: GST
• Form: Liquid
• Bio-activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate, Mg(or Mn)/ATP, and Ca/Calmodulin. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip TM3000. Substrate: GS peptide. ATP: 100 μM.
• Molecular Mass: 85 kDa
• Purity: 63 % by SDS-PAGE/CBB staining
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)

Gene Information

• Gene Name: CAMK2G calcium/calmodulin-dependent protein kinase II gamma [ Homo sapiens ]
• Official Symbol: CAMK2G
• Synonyms: CAMK2G; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin dependent protein kinase (CaM kinase) II gamma, CAMKG; calcium/calmodulin-dependent protein kinase type II subunit gamma; caMK-II subunit gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; CAMK; CAMKG; CAMK-II; FLJ16043; MGC26678
• Gene ID: 818
• mRNA Refseq: NM_001204492
• Protein Refseq: NP_001191421
• MIM: 602123
• UniProt ID: Q13555