Recombinant Human CAMKK2 Protein, MYC/DDK-tagged

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Recombinant Human CAMKK2 Protein, MYC/DDK-tagged

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Cat.No. : CAMKK2-2490H
Product Overview : Recombinant Human CAMKK2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 59.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta [ Homo sapiens ]
Official Symbol : CAMKK2
Synonyms : CAMKK; CAMKKB
Gene ID : 10645
mRNA Refseq : NM_006549
Protein Refseq : NP_006540
UniProt ID : Q96RR4

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