Recombinant Human CAMLG Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CAMLG-1925H |
Product Overview : | CAMLG MS Standard C13 and N15-labeled recombinant protein (NP_001736) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 33 kDa |
AA Sequence : | MESMAVATDGGERPGVPAGSGLSAS QRRAELRRRKLLMNSEQRINRIMGF HRPGSGAEEESQTKSKQQDSDKLNS LSVPSVSKRVVLGDSVSTGTTDQQG GVAEVKGTQLGDKLDSFIKPPECSS DVNLELRQRNRGDLTADSVQRGSRH GLEQYLSRFEEAMKLRKQLISEKPS QEDGNTTEEFDSFRIFRLVGCALLA LGVRAFVCKYLSIFAPFLTLQLAYM GLYKYFPKSEKKIKTTVLTAALLLS GIPAEVINRSMDTYSKMGEVFTDLC VYFFTFIFCHELLDYWGSEVPTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CAMLG calcium modulating ligand [ Homo sapiens (human) ] |
Official Symbol : | CAMLG |
Synonyms : | CAMLG; calcium modulating ligand; calcium signal-modulating cyclophilin ligand; calcium modulating cyclophilin ligand; calcium signal modulating cyclophilin ligand; CAML; cyclophilin B binding protein; cyclophilin B-binding protein; calcium-modulating cyclophilin ligand; calcium-signal modulating cyclophilin ligand; MGC163197; |
Gene ID : | 819 |
mRNA Refseq : | NM_001745 |
Protein Refseq : | NP_001736 |
MIM : | 601118 |
UniProt ID : | P49069 |
Products Types
◆ Recombinant Protein | ||
Camlg-584R | Recombinant Rat Camlg Protein, His/GST-tagged | +Inquiry |
Caml-755M | Recombinant Mouse Caml Protein, MYC/DDK-tagged | +Inquiry |
CAMLG-1202M | Recombinant Mouse CAMLG Protein, His (Fc)-Avi-tagged | +Inquiry |
Caml-583M | Recombinant Mouse Caml Protein, His-tagged | +Inquiry |
CAMLG-0344H | Recombinant Human CAMLG Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CAMLG-7872HCL | Recombinant Human CAMLG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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