| Description : |
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
76.3 kDa |
| AA Sequence : |
MADRRRQRASQDTEDEESGASGSDS GGSPLRGGGSCSGSAGGGGSGSLPS QRGGRTGALHLRRVESGGAKSAEES ECESEDGIEGDAVLSDYESAEDSEG EEGEYSEEENSKVELKSEANDAVNS STKEEKGEEKPDTKSTVTGERQSGD GQESTEPVENKVGKKGPKHLDDDED RKNPAYIPRKGLFFEHDLRGQTQEE EVRPKGRQRKLWKDEGRWEHDKFRE DEQAPKSRQELIALYGYDIRSAHNP DDIKPRRIRKPRYGSPPQRDPNWNG ERLNKSHRHQGLGGTLPPRTFINRN AAGTGRMSAPRNYSRSGGFKEGRAG FRPVEAGGQHGGRSGETVKHEISYR SRRLEQTSVRDPSPEADAPVLGSPE KEEAASEPPAAAPDAAPPPPDRPIE KKSYSRARRTRTKVGDAVKLAEEVP PPPEGLIPAPPVPETTPTPPTKTGT WEAPVDSSTSGLEQDVAQLNIAEQN WSPGQPSFLQPRELRGMPNHIHMGA GPPPQFNRMEEMGVQGGRAKRYSSQ RQRPVPEPPAPPVHISIMEGHYYDP LQFQGPIYTHGDSPAPLPPQGMLVQ PGMNLPHPGLHPHQTPAPLPNPGLY PPPVSMSPGQPPPQQLLAPTYFSAP GVMNFGNPSYPYAPGALPPPPPPHL YPNTQAPSQVYGGVTYYNPAQQQVQ PKPSPPRRTPQPVTIKPPPPEVVSR GSSTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
