Recombinant Human CASC4 Protein, GST-Tagged

• Cat.No.: CASC4-0409H
• Product Overview: Human CASC4 full-length ORF (NP_612432.2, 1 a.a. - 436 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 75.9 kDa
• AA Sequence: MVGFGANRRAGRLPSLVLVVLLVVI VVLAFNYWSISSRHVLLQEEVAELQ GQVQRTEVARGRLEKRNSDLLLLVD THKKQIDQKEADYGRLSSRLQAREG LGKRCEDDKVKLQNNISYQMADIHH LKEQLAELRQEFLRQEDQLQDYRKN NTYLVKRLEYESFQCGQQMKELRAQ HEENIKKLADQFLEEQKQETQKIQS NDGKELDINNQVVPKNIPKVAENVA DKNEEPSSNHIPHGKEQIKRGGDAG MPGIEENDLAKVDDLPPALRKPPIS VSQHESHQAISHLPTGQPLSPNMPP DSHINHNGNPGTSKQNPSSPLQRLI PGSNLDSEPRIQTDILKQATKDRVS DFHKLKQSRFFDENESPVDPQHGSK LADYNGDDGNVGEYEADKQAELAYN EEEDGDGGEEDVQDDEERELQMDPA DYGKQHFNDVL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CASC4 cancer susceptibility candidate 4 [ Homo sapiens ]
• Official Symbol: CASC4
• Synonyms: CASC4; cancer susceptibility candidate 4; protein CASC4; DKFZp459F1927; H63; gene associated with HER-2/neu overexpression; cancer susceptibility candidate gene 4 protein; MGC74708
• Gene ID: 113201
• mRNA Refseq: NM_138423
• Protein Refseq: NP_612432
• UniProt ID: Q6P4E1