| Description : |
This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
104.3 kDa |
| AA Sequence : |
MADDDVLFEDVYELCEVIGKGPFSV VRRCINRETGQQFAVKIVDVAKFTS SPGLSTEDLKREASICHMLKHPHIV ELLETYSSDGMLYMVFEFMDGADLC FEIVKRADAGFVYSEAVASHYMRQI LEALRYCHDNNIIHRDVKPHCVLLA SKENSAPVKLGGFGVAIQLGESGLV AGGRVGTPHFMAPEVVKREPYGKPV DVWGCGVILFILLSGCLPFYGTKER LFEGIIKGKYKMNPRQWSHISESAK DLVRRMLMLDPAERITVYEALNHPW LKERDRYAYKIHLPETVEQLRKFNA RRKLKGAVLAAVSSHKFNSFYGDPP EELPDFSEDPTSSGLLAAERAVSQV LDSLEEIHALTDCSEKDLDFLHSVF QDQHLHTLLDLYDKINTKSSPQIRN PPSDAVQRAKEVLEEISCYPENNDA KELKRILTQPHFMALLQTHDVVAHE VYSDEALRVTPPPTSPYLNGDSPES ANGDMDMENVTRVRLVQFQKNTDEP MGITLKMNELNHCIVARIMHGGMIH RQGTLHVGDEIREINGISVANQTVE QLQKMLREMRGSITFKIVPSYRTQS SSCERDSPSTSRQSPANGHSSTNNS VSDLPSTTQPKGRQIYVRAQFEYDP AKDDLIPCKEAGIRFRVGDIIQIIS KDDHNWWQGKLENSKNGTAGLIPSP ELQEWRVACIAMEKTKQEQQASCTW FGKKKKQYKDKYLAKHNAVFDQLDL VTYEEVVKLPAFKRKTLVLLGAHGV GRRHIKNTLITKHPDRFAYPIPHTT RPPKKDEENGKNYYFVSHDQMMQDI SNNEYLEYGSHEDAMYGTKLETIRK IHEQGLIAILDVEPQALKVLRTAEF APFVVFIAAPTITPGLNEDESLQRL QKESDILQRTYAHYFDLTIINNEID ETIRHLEEAVELVCTAPQWVPVSWV YTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
