Recombinant Human CASP3 protein, His/MBP-tagged
Cat.No. : | CASP3-293H |
Product Overview : | Recombinant Human CASP3(1-113 aa) fused with His/MBP tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
Source : | E. coli |
Species : | Human |
Tag : | His/MBP |
Form : | Liquid in PBS |
Protein length : | 1-113 aa |
Purity : | SDS-PAGE >90% |
Applications : | WB Positive Control |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | CASP3 caspase 3, apoptosis-related cysteine peptidase [ Homo sapiens ] |
Official Symbol : | CASP3 |
Synonyms : | CASP3; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis related cysteine protease; caspase-3; apopain; CPP32; CPP32B; Yama; CASP-3; CPP-32; procaspase3; protein Yama; PARP cleavage protease; cysteine protease CPP32; SREBP cleavage activity 1; caspase 3, apoptosis-related cysteine protease; SCA-1; |
Gene ID : | 836 |
mRNA Refseq : | NM_004346 |
Protein Refseq : | NP_004337 |
MIM : | 600636 |
UniProt ID : | P42574 |
Products Types
◆ Recombinant Protein | ||
CASP3-0595H | Recombinant Human CASP3 Protein (M1-H277), His/Strep tagged | +Inquiry |
CASP3-01H | Active Recombinant Human CASP3 Protein, His-tagged | +Inquiry |
Casp3-771M | Recombinant Mouse Casp3 Protein, MYC/DDK-tagged | +Inquiry |
CASP3-625H | Recombinant Human CASP3 Protein, His-tagged | +Inquiry |
CASP3-110C | Recombinant Cynomolgus Monkey CASP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CASP3-7839HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
CASP3-7838HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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