Recombinant Human CASP9 Protein (Lys100-270Thr), SUMO tagged
Cat.No. : | CASP9-0864H |
Product Overview : | Recombinant human Caspase 9 (Lys100-270Thr) fused with SUMO tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
Source : | E. coli |
Species : | Human |
Tag : | SUMO |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 34.58 kDa |
Protein Length : | Lys100-270Thr |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | CASP9 caspase 9, apoptosis-related cysteine peptidase [ Homo sapiens (human) ] |
Official Symbol : | CASP9 |
Synonyms : | CASP9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis related cysteine protease; caspase-9; APAF 3; ICE LAP6; MCH6; PPP1R56; protein phosphatase 1; regulatory subunit 56; apoptotic protease MCH-6; ICE-like apoptotic protease 6; apoptotic protease activating factor 3; protein phosphatase 1, regulatory subunit 56; APAF3; APAF-3; ICE-LAP6; CASPASE-9c; |
Gene ID : | 842 |
mRNA Refseq : | NM_001229 |
Protein Refseq : | NP_001220 |
MIM : | 602234 |
UniProt ID : | P55211 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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