Recombinant Human Cathepsin S

• Cat.No.: CTSS-1651H
• Product Overview: Recombinant human CTSS was expressed by Human spleen.

Specification

• Cat. No.: CTSS-1651H
• Description: Like Cathepsins B, H, and L, CTSS belongs to the group of lysosomal cysteine proteinases. CTSS is found primarily in the spleen and in lung macrophages. Its level is elevated in the brain tissue of those with Alzheimer"s disease and Down syndrome. CTSS may function in the processing of amyloid precursor protein to amyloid beta peptides.
• Biological Activity: 229.9 mU/mg using the method described by Kirche & Weiderlanders in Methods in Enzymology, 244.
• Source: Human spleen
• Species: Human
• Form: Lyophilized from 8.36 ul of 100 mM NaAc+1 mM EDTA, pH 5.5.
• Appearance: Lyophilized
• Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
• Storage: Store at -70°C, stable for at least 1 year as supplied. Avoid freeze/thaw cycles.
• Pathways: Antigen processing and presentation; Lysosome; Phagosome; Tuberculosis

Gene Information

• Gene Name: CTSS cathepsin S [ Homo sapiens ]
• Official Symbol: CTSS
• Synonyms: CTSS; cathepsin S; MGC3886; FLJ50259; OTTHUMP00000032942; EC 3.4.22.27
• Gene ID: 1520
• mRNA Refseq: NM_004079
• Protein Refseq: NP_004070
• MIM: 116845
• UniProt ID: P25774
• Chromosome Location: 1q21
• Function: cysteine-type endopeptidase activity; peptidase activity