Recombinant Human CCDC40 Protein, GST-tagged

• Cat.No.: CCDC40-5171H
• Product Overview: Human CCDC40 full-length ORF ( XP_939608.1, 1 a.a. - 478 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is necessary for motile cilia function. It functions in correct left-right axis formation by regulating the assembly of the inner dynein arm and the dynein regulatory complexes, which control ciliary beat. Mutations in this gene cause ciliary dyskinesia type 15, a disorder due to defects in cilia motility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.7 kDa
• AA Sequence: MAEPGGAAGRSHPEDGSASEGEKEG NNESHMVSPPEKDDGQKGEEAVGST EHPEEVTTQAEAAIEEGEVETEGEA AVEGEEEAVSYGDAESEEEYYYTET SSPEGQISAADTTYPYFSPPQELPG EEAYDSVSGEAGLQGFQQEATGPPE SRERRVTSPEPSHGVLGPSEQMGQV TSGPAVGRLTGSTEEPQGQVLPMGV QHRFRLSHGSDIESSDLEEFVSQEP VIPPGVPDAHPREGDLPVFQDQIQQ PSTEEGAMAERVESEGSDEEAEDEG SQLVVLDPDHPLMVRFQAALKNYLN RQIEKLKLDLQELVVATKQSRAQRQ ELGVNLYEVQQHLVHLQKLLEKSHD RHAMASSERRQKEEELQAARALYTK TCAAANEERKKLAALQTEMENLALH LFYMQNIDQDMRDDIRVMTQVVKKA ETERIRAEIEKKKQGVGDTGAAFIP KTTQGDQVSGRGKKKPGTVVARVSP AEL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCDC40 coiled-coil domain containing 40 [ Homo sapiens (human) ]
• Official Symbol: CCDC40
• Synonyms: CCDC40; coiled-coil domain containing 40; CILD15; FAP172; coiled-coil domain-containing protein 40
• Gene ID: 55036
• mRNA Refseq: NM_001243342
• Protein Refseq: NP_001230271
• MIM: 613799
• UniProt ID: Q4G0X9