Recombinant Human CCDC88B, GST-tagged

• Cat.No.: CCDC88B-10822H
• Product Overview: Recombinant Human CCDC88B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-99a.a.
• Description: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CCDC88B coiled-coil domain containing 88B [ Homo sapiens ]
• Official Symbol: CCDC88B
• Synonyms: CCDC88B; coiled-coil domain containing 88B; CCDC88, coiled coil domain containing 88; coiled-coil domain-containing protein 88B; brain leucine zipper protein; BRLZ; FLJ00354; FLJ37970; HkRP3; hook-related protein 3; brain leucine zipper domain-containing protein; 78 kDa glucose-regulated protein [GRP78]-interacting protein induced by ER stress; HKRP3; gipie; CCDC88; DKFZp434G0920
• Gene ID: 283234
• mRNA Refseq: NM_032251
• Protein Refseq: NP_115627
• MIM: 611205
• UniProt ID: A6NC98
• Chromosome Location: 11q13.1
• Function: microtubule binding