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Recombinant Human CCR3 Protein, GST-Tagged

Cat.No. : CCR3-0691H
Product Overview : Human CCR3 full-length ORF (NP_001828.1, 1 a.a. - 355 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 67.4 kDa
AA Sequence : MTTSLDTVETFGTTSYYDDVGLLCE KADTRALMAQFVPPLYSLVFTVGLL GNVVVVMILIKYRRLRIMTNIYLLN LAISDLLFLVTLPFWIHYVRGHNWV FGHGMCKLLSGFYHTGLYSEIFFII LLTIDRYLAIVHAVFALRARTVTFG VITSIVTWGLAVLAALPEFIFYETE ELFEETLCSALYPEDTVYSWRHFHT LRMTIFCLVLPLLVMAICYTGIIKT LLRCPSKKKYKAIRLIFVIMAVFFI FWTPYNVAILLSSYQSILFGNDCER SKHLDLVMLVTEVIAYSHCCMNPVI YAFVGERFRKYLRHFFHRHLLMHLG RYIPFLPSEKLERTSSVSPSTAEPE LSIVF
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CCR3 chemokine (C-C motif) receptor 3 [ Homo sapiens ]
Official Symbol : CCR3
Synonyms : CCR3; chemokine (C-C motif) receptor 3; CMKBR3; C-C chemokine receptor type 3; CC CKR 3; CD193; CKR3; CCR-3; C-C CKR-3; b-chemokine receptor; CC chemokine receptor 3; eosinophil eotaxin receptor; eosinophil CC chemokine receptor 3; CC-CKR-3; MGC102841;
Gene ID : 1232
mRNA Refseq : NM_001164680
Protein Refseq : NP_001158152
MIM : 601268
UniProt ID : P51677

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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06/28/2020

    Implementing protein reagents reduces operational risks in experiments, thereby improving experimental safety.

    11/23/2019

      Manufacturers of protein reagents are committed to product innovation and improvement, continuously elevating quality standards.

      09/22/2019

        Protein reagents exhibit stable quality, providing consistent experimental results and reliable data.

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