Recombinant Human CCR4 Protein (1-360 aa), His-tagged
| Cat.No. : | CCR4-2724H |
| Product Overview : | Recombinant Human CCR4 Protein (1-360 aa) is produced by in vitro E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal. Protein Description: Full Length. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His |
| Protein Length : | 1-360 aa |
| Description : | High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 44.9 kDa |
| AA Sequence : | MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL |
| Purity : | > 85% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Gene Name | CCR4 chemokine (C-C motif) receptor 4 [ Homo sapiens ] |
| Official Symbol | CCR4 |
| Synonyms | CCR4; CC CKR 4; CD194; ChemR13; CKR4; CMKBR4; k5 5; CCR-4; C-C CKR-4; K5-5; CC-CKR-4; HGCN:14099; MGC88293; |
| Gene ID | 1233 |
| mRNA Refseq | NM_005508 |
| Protein Refseq | NP_005499 |
| MIM | 604836 |
| UniProt ID | P51679 |
Not For Human Consumption!
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