Recombinant Human CCR4 Protein

• Cat.No.: CCR4-0692H
• Product Overview: Human CCR4 full-length ORF (NP_005499.1) recombinant protein without tag.

Specification

• Description: The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 41.4 kDa
• AA Sequence: MNPTDIADTTLDESIYSNYYLYESI PKPCTKEGIKAFGELFLPPLYSLVF VFGLLGNSVVVLVLFKYKRLRSMTD VYLLNLAISDLLFVFSLPFWGYYAA DQWVFGLGLCKMISWMYLVGFYSGI FFVMLMSIDRYLAIVHAVFSLRART LTYGVITSLATWSVAVFASLPGFLF STCYTERNHTYCKTKYSLNSTTWKV LSSLEINILGLVIPLGIMLFCYSMI IRTLQHCKNEKKNKAVKMIFAVVVL FLGFWTPYNIVLFLETLVELEVLQD CTFERYLDYAIQATETLAFVHCCLN PIIYFFLGEKFRKYILQLFKTCRGL FVLCQYCGLLQIYSADTPSSSYTQS TMDHDLHDAL
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: CCR4 chemokine (C-C motif) receptor 4 [ Homo sapiens ]
• Official Symbol: CCR4
• Synonyms: CCR4; chemokine (C-C motif) receptor 4; C-C chemokine receptor type 4; CC CKR 4; CD194; ChemR13; CKR4; CMKBR4; k5 5; CCR-4; C-C CKR-4; chemokine (C-C) receptor 4; K5-5; CC-CKR-4; HGCN:14099; MGC88293
• Gene ID: 1233
• mRNA Refseq: NM_005508
• Protein Refseq: NP_005499
• MIM: 604836
• UniProt ID: P51679