Recombinant Human CCT3 Protein, GST-Tagged

• Cat.No.: CCT3-0711H
• Product Overview: Human CCT3 full-length ORF (AAH08019.1, 1 a.a. - 544 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 86.8 kDa
• AA Sequence: MGHRPVLVLSQNTKRESGRKVQSGN INAAKTIADIIRTCLGPKSMMKMLL DPMGGIVMTNDGNAILREIQVQHPA AKSMIEISRTQDEEVGDGTTSVIIL AGEMLSVAEHFLEQQMHPTVVISAY RKALDDMISTLKKISIPVDISDSDM MLNIINSSITTKAISRWSSLACNIA LDAVKMVQFEENGRKEIDIKKYARV EKIPGGIIEDSCVLRGVMINKDVTH PRMRRYIKNPRIVLLDSSLEYKKGE SQTDIEITREEDFTRILQMEEEYIQ QLCEDIIQLKPDVVITEKGISDLAQ HYLMRANITAIRRVRKTDNNRIARA CGARIVSRPEELREDDVGTGAGLLE IKKIGDEYFTFITDCKDPKACTILL RGASKEILSEVERNLQDAMQVCRNV LLDPQLVPGGGASEMAVAHALTEKS KAMTGVEQWPYRAVAQALEVIPRTL IQNCGASTIRLLTSLRAKHTQENCE TWGVNGETGTLVDMKELGIWEPLAV KLQTYKTAVETAVLLLRIDDIVSGH KKKGDDQSRQGGAPDAGQE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCT3 chaperonin containing TCP1, subunit 3 (gamma) [ Homo sapiens ]
• Official Symbol: CCT3
• Synonyms: CCT3; chaperonin containing TCP1, subunit 3 (gamma); TRIC5; T-complex protein 1 subunit gamma; Cctg; hTRiC5; T-complex protein 1, gamma subunit; TCP1 (t-complex-1) ring complex, polypeptide 5; CCTG; PIG48; CCT-gamma; TCP-1-gamma
• Gene ID: 7203
• mRNA Refseq: NM_001008800
• Protein Refseq: NP_001008800
• MIM: 600114
• UniProt ID: P49368