Recombinant Human CD160 Protein, His-Tagged

• Cat.No.: CD160-01H
• Product Overview: Recombinant Human CD160 Protein, His-Tagged was expressed in Baculovirus cell line

Specification

• Description: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
• Source: Baculovirus
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 15.9 kDa
• Protein length: 142aa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Usage: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by absorbance at 280nm)
• Storage Buffer: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: CD160 CD160 molecule [ Homo sapiens (human) ]
• Official Symbol: CD160
• Synonyms: CD160 antigen, CD160, BY55, NK1, NK28
• Gene ID: 11126
• mRNA Refseq: NM_007053.4
• Protein Refseq: NP_008984.1
• MIM: 604463
• UniProt ID: O95971