Recombinant Human CD19 Protein (20-291), C-His-tagged
Cat.No. : | CD19-26H |
Product Overview : | Recombinant human CD19 (20-291) was expressed in CHO cells using a C-terminal His tag. |
- Specification
- Gene Information
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Description : | B-lymphocyte antigen CD19 is a type I transmembrane protein present on all B cells and is a dominant signaling component of mature B cells. CD19 acts as a critical coreceptor for B cell receptor (BCR) signal transduction by recruiting and amplifying the activation of Src-family protein tyrosine kinases such as Lyn and Fyn. CD19 also enhances BCR-induced signaling crucial for B cell expansion through recruitment and activation of PI3K and downstream AKT kinases. CD19-deficient humans and mice exhibit hypo-responsiveness to transmembrane signals, and weak T cell-dependent humoral responses, leading to an overall impaired immune response. |
Source : | CHO |
Species : | Human |
Tag : | C-His |
Molecular Mass : | Observed MW: ~50-65 kDa. Calculated MW: ~31 kDa. |
Protein Length : | 20-291 |
Purity : | The purity of CD19 was determined to be ~ 75 % by densitometry. |
Stability : | One year at -70 centigrade from date of shipment. |
Storage : | Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 μg/μL |
Storage Buffer : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.25mM DTT, 25% glycerol. |
Shipping : | Dry ice |
Gene Name : | CD19 CD19 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD19 |
Synonyms : | CD19; CD19 molecule; CD19 antigen; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4; B4; CVID3; MGC12802; |
Gene ID : | 930 |
mRNA Refseq : | NM_001178098 |
Protein Refseq : | NP_001171569 |
MIM : | 107265 |
UniProt ID : | P15391 |
Products Types
◆ Lysates | ||
CD19-2005HCL | Recombinant Human CD19 cell lysate | +Inquiry |
CD19-2164MCL | Recombinant Mouse CD19 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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