Active Recombinant Human CD274 protein, His/Fc-tagged, Biotinylated
| Cat.No. : | CD274-8230H |
| Product Overview : | Recombinant Human CD274(Phe 19 - Arg 238) fused with His/Fc tag at C-terminal was expressed in HEK293. Biotinylated. |
- Specification
- Gene Information
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| Source : | HEK293 |
| Species : | Human |
| Tag : | His/Fc |
| Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
| Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Human PD-1, Fc Tag at 2 μg/mL can bind Biotinylated Human PD-L1, His Tag & Fc Tag with a linear range of 0.01-1 μg/mL. |
| Protein length : | Phe 19 - Arg 238 |
| Endotoxin : | Less than 1.0 EU per μg of the Biotinylated Human PD-L1, His Tag & Fc tag by the LAL method. |
| Purity : | >95% as determined by SDS-PAGE. |
| Applications : | ELISA, western blotting, inhibition assay, pull-down, SPR, FACS, and affinity purification, together with anti-biotin antibody, streptavidin or avidin-conjugated probes. |
| Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade). |
| Gene Name : | CD274 CD274 molecule [ Homo sapiens ] |
| Official Symbol : | CD274 |
| Synonyms : | CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296; |
| Gene ID : | 29126 |
| mRNA Refseq : | NM_014143 |
| Protein Refseq : | NP_054862 |
| MIM : | 605402 |
| UniProt ID : | Q9NZQ7 |
| Chromosome Location : | 9p24.1 |
| Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem; |
| Function : | protein binding; protein tyrosine phosphatase activity; receptor activity; |
Products Types
| ◆ Lysates | ||
| CD274-914CCL | Recombinant Cynomolgus CD274 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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