| Description : |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
25.2 kDa |
| Protein Length : |
534 |
| AA Sequence : |
MLRRRGSPGMGVHVGAALGALWFCL TGALEVQVPEDPVVALVGTDATLCC SFSPEPGFSLAQLNLIWQLTDTKQL VHSFAEGQDQGSAYANRTALFPDLL AQGNASLRLQRVRVADEGSFTCFVS IRDFGSAAVSLQVAAPYSKPSMTLE PNKDLRPGDTVTITCSSYQGYPEAE VFWQDGQGVPLTGNVTTSQMANEQG LFDVHSILRVVLGANGTYSCLVRNP VLQQDAHSSVTITPQRSPTGAVEVQ VPEDPVVALVGTDATLRCSFSPEPG FSLAQLNLIWQLTDTKQL VHSFTEGRDQGSAYANRTALFPDLLAQGNASL RLQRVRVADEGSFTCFVS IRDFGSAAVSLQVAAPYSKPSMTLE PNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQ GVPLTGNVTTSQMANEQG LFDVHSVLRVVLGANGTYSCLVRNPVLQQDAH GSVTITGQPMTFPPEALWVTVGLSV CLIALLVALAFVCWRKIKQSCEEEN AGAEDQDGEGEGSKTALQPLKHSDS KEDDGQEIA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
