Recombinant Human CD276 protein, His-Avi-tagged, Biotinylated

• Cat.No.: CD276-126HB
• Product Overview: Biotinylated Recombinant Human B7-H3b Protein is expressed from Expi293 with a His and Avi Tag at the Cterminal. It contains Gly27 - Thr461.

Specification

• Description: B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma ) production, and cytotoxic T cells induction.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 49.5 kDa.Due to glycosylation, the protein migrates to 70-80 KDa based on Bis-Tris PAGE result
• Protein length: It contains Gly27 - Thr461.
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CD276 CD276 molecule [ Homo sapiens ]
• Official Symbol: CD276
• Synonyms: B7H3; B7-H3; CD276 antigen; CD276 molecule; CD276; B7H34Ig-B7-H3; B7-H3B7 homolog 3; Costimulatory molecule
• Gene ID: 80381
• mRNA Refseq: NM_001024736
• Protein Refseq: NP_001019907
• MIM: 605715
• UniProt ID: Q5ZPR3