Recombinant Human CD276 protein, His-Avi-tagged, Biotinylated

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Recombinant Human CD276 protein, His-Avi-tagged, Biotinylated

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Cat.No. : CD276-126HB
Product Overview : Biotinylated Recombinant Human B7-H3b Protein is expressed from Expi293 with a His and Avi Tag at the Cterminal. It contains Gly27 - Thr461.
Description : B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma ) production, and cytotoxic T cells induction.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 49.5 kDa.Due to glycosylation, the protein migrates to 70-80 KDa based on Bis-Tris PAGE result
Protein length : It contains Gly27 - Thr461.
Endotoxin : Less than 0.05 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

Gene Name : CD276 CD276 molecule [ Homo sapiens ]
Official Symbol : CD276
Synonyms : B7H3; B7-H3; CD276 antigen; CD276 molecule; CD276; B7H34Ig-B7-H3; B7-H3B7 homolog 3; Costimulatory molecule
Gene ID : 80381
mRNA Refseq : NM_001024736
Protein Refseq : NP_001019907
MIM : 605715
UniProt ID : Q5ZPR3

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