Recombinant Human CD276 protein, His-tagged
Cat.No. : | CD276-348H |
Product Overview : | Recombinant Human CD276 protein (Leu29-Pro245), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293). |
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Description : | B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 25.2 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 217 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD276 |
Official Symbol : | CD276 |
Synonyms : | CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3 |
Gene ID : | 80381 |
mRNA Refseq : | NM_001024736 |
Protein Refseq : | NP_001019907 |
MIM : | 605715 |
UniProt ID : | Q5ZPR3 |
Products Types
◆ Recombinant Protein | ||
CD276-27H | Recombinant Human CD276 Protein (ECD), His-tagged(C-ter) | +Inquiry |
CD276-145H | Recombinant Human CD276 Protein, C-His-tagged | +Inquiry |
CD276-601M | Recombinant Mouse CD276 Protein | +Inquiry |
CD276-1363H | Recombinant Human CD276 protein(Met1-Thr461), hFc-tagged, Biotinylated | +Inquiry |
CD276-599H | Recombinant Human CD276 Protein | +Inquiry |
◆ Lysates | ||
CD276-001MCL | Recombinant Mouse CD276 cell lysate | +Inquiry |
CD276-1959HCL | Recombinant Human CD276 cell lysate | +Inquiry |
CD276-826RCL | Recombinant Rat CD276 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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