Recombinant Human CD28 Protein, Fc-tagged, Alexa Fluor 488 conjugated
Cat.No. : | CD28-3909HAF488 |
Product Overview : | Alexa Fluor 488 conjugated recombinant human CD28 (P10747-1) isoform 1 extracellular domain (Met 1-Pro 152), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell. |
Availability | October 07, 2024 |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | The recombinant human CD28/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 375 amino acids and predictes a molecular mass of 42 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD28/Fc monomer is approximately 55-65 kDa due to glycosylation. |
Protein length : | 375 |
Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 488 via amines Excitation Wavelength: 488 nm Emission Wavelength: 515-545 nm |
Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4 |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | CD28 CD28 molecule [ Homo sapiens ] |
Official Symbol : | CD28 |
Gene ID : | 940 |
mRNA Refseq : | NM_001243077 |
Protein Refseq : | NP_001230006 |
MIM : | 186760 |
UniProt ID : | P10747 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIts unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.
Q&As (5)
Ask a questionCD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.
Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.
CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.
CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.
Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.
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