Recombinant Human CD2AP Protein, His-tagged

Cat.No. : CD2AP-151H
Product Overview : Recombinant Human CD2 associated protein(CD2AP)(NM_012120), with a His tag, was expressed in human cells.
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  • Gene Information
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Description : This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.159, without any preservatives.
Molecular Mass : 71.3 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : CD2AP CD2-associated protein [ Homo sapiens ]
Official Symbol : CD2AP
Synonyms : CD2AP; CD2-associated protein; CMS; adapter protein CMS; cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; DKFZp586H0519;
Gene ID : 23607
mRNA Refseq : NM_012120
Protein Refseq : NP_036252
MIM : 604241
UniProt ID : Q9Y5K6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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