Recombinant Human CD55 Protein (35-353aa), C-His-tagged
Cat.No. : | CD55-01H |
Product Overview : | Recombinant human CD55 (35-353aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Availability | July 27, 2024 |
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Description : | This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. |
Source : | Baculovirus |
Species : | Human |
Tag : | His |
Form : | Liquid |
Molecular Mass : | 36 kDa (328aa) |
Protein Length : | 35-353 |
AA Sequence : | ADPDCGLPPDVPNAQPALEGRTSFP EDTVITYKCEESFVKIPGEKDSVIC LKGSQWSDIEEFCNRSCEVPTRLNS ASLKQPYITQNYFPVGTVVEYECRP GYRREPSLSPKLTCLQNLKWSTAVE FCKKKSCPNPGEIRNGQIDVPGGIL FGATISFSCNTGYKLFGSTSSFCLI SGSSVQWSDPLPECREIYCPAPPQI DNGIIQGERDHYGYRQSVTYACNKG FTMIGEHSIYCTVNNDEGEWSGPPP ECRGKSLTSKVPPTVQKPTTVNVPT TEVSPTSQKTTTKTTTPNAQATRST PVSRTTKHFHETTPNKGSGTTSHHH HHH |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 95% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by BCA assay) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | CD55 CD55 molecule (Cromer blood group) [ Homo sapiens (human) ] |
Official Symbol : | CD55 |
Synonyms : | CD55; CD55 molecule (Cromer blood group); CR; TC; DAF; CROM; CHAPLE; complement decay-accelerating factor; CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cromer blood group antigen; Rh blood group D antigen |
Gene ID : | 1604 |
mRNA Refseq : | NM_000574 |
Protein Refseq : | NP_000565 |
MIM : | 125240 |
UniProt ID : | P08174 |
Products Types
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CD55-2325H | Recombinant Human CD55 Protein, GST-tagged | +Inquiry |
Cd55-7485R | Recombinant Rat Cd55 protein(Met1-Ser371), hFc-tagged | +Inquiry |
CD55-164H | Recombinant Human CD55 Protein, His-tagged | +Inquiry |
Cd55-6893M | Recombinant Mouse Cd55 protein(Met1-Thr361), His-tagged | +Inquiry |
CD55-689H | Recombinant Human CD55 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD55-2531HCL | Recombinant Human CD55 cell lysate | +Inquiry |
CD55-1433RCL | Recombinant Rat CD55 cell lysate | +Inquiry |
CD55-1669MCL | Recombinant Mouse CD55 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewEfficient shipping and exceptional product quality. This company knows how to serve its customers.
Consistency is key in research, and this product delivers that every time.
We've tried various proteins, but this one stands out for its purity and performance.
Q&As (5)
Ask a questionGenetic variations in CD55 may influence susceptibility to complement-mediated disorders by affecting the protein's ability to regulate complement activation. This can lead to conditions like paroxysmal nocturnal hemoglobinuria (PNH).
CD55 has immunomodulatory functions beyond complement regulation, influencing T cell responses and contributing to the maintenance of immune tolerance.
CD55 protects cells from complement-mediated lysis by preventing the formation of membrane attack complexes. This contributes to immune evasion by pathogens and self-cells alike.
CD55 consists of extracellular domains responsible for interactions with complement proteins, particularly C3b and C4b. These interactions prevent the formation of membrane attack complexes on host cells.
CD55 dysregulation is associated with autoimmune disorders, where it may contribute to immune system overactivity. Additionally, some pathogens exploit CD55 to evade host immune responses.
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