Recombinant Human CD80 protein, His-Avi-tagged

• Cat.No.: CD80-190H
• Product Overview: Recombinant Human CD80/B7-1 Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal. It contains Val35-Asn242.

Specification

• Description: Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
• Molecular Mass: The protein has a predicted MW of 26. 8 kDa. Due to glycosylation, the protein migrates to 50- 70KDa based on Bis-Tris PAGE result.
• Protein length: It contains Val35-Asn242.
• Endotoxin: Less than 0. 05EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CD80 CD80 molecule [ Homo sapiens ]
• Official Symbol: CD80
• Synonyms: CD80 antigen; CD80 molecule; B7; B71; B7-1; Activation B7-1 antigen; BB1; CD28LG1; CD28LGB7-1 antigen); CD80; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7. 1; T-lymphocyte activation antigen CD80
• Gene ID: 941
• mRNA Refseq: NM_005191
• Protein Refseq: NP_005182
• MIM: 112203
• UniProt ID: P33681