|Official Full Name||CD80 antigen|
|Background||Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode of action is by bindin|
|Synonyms||CD80; CD80 antigen; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17; T-lymphocyte activation antigen CD80; B7 protein; activation B7-1 antigen; B7; BB1; LAB7; CD28LG; CD28LG1; OTTHUMP00000215214; OTTHUMP00000215215; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cd80 involved in several pathways and played different roles in them. We selected most pathways cd80 participated on our site, such as Cell adhesion molecules (CAMs), Toll-like receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd80 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell adhesion molecules (CAMs)||CLDN19; CLDN15LB; HLA-A; CADM1B; HLA-DRB4; CD8B; CDH5; GLYCAM1; PECAM1; CLDN15|
|Toll-like receptor signaling pathway||TLR2-2; MAP2K3; TLR8; MAPK11; MAPK8; IRF3; TAB2; TICAM2; CCL4L2; TLR2-1|
|Intestinal i||HLA-DRB3; CCL27B; IL-15RA; AICDA; MAP3K14; CD86; MHC2DAB; HLA-DRA; HLA-DQA2; HLA-DPA1|
|ne network for IgA production||CCR10; CXCL12B; CXCR4; HLA-DOA; ITGB7; ITGA4; HLA-DQB1; IL6; IL-15RA; IL5|
|Type I diabetes mellitus||INS; LTA; IL12A; GZMB; INS2; HLA-B; HLA-DRB1; HLA-DRB3; GAD1; HLA-DRB4|
|Autoi||IFNA4; TSHR; HLA-DRA; IFNA5; HLA-DQA1; IFNA1; IFNA16; CD80; FASLG; H2-Q10|
|ne thyroid disease||HLA-DRB5; HLA-F; HLA-C; IFNA2; HLA-A; CD80; IFNA16; IFNA5; CD40; H2-AA|
|Systemic lupus erythematosus||GRIN2A; HIST1H2BK; HLA-DRB3; HIST1H2BC; H2AFZ; SNRPB; HIST1H2BA; HIST1H3F; GRIN2B; TRIM21|
|Rheumatoid arthritis||ANGPT1; ATP6V1G2; LTB; ATP6V1H; IL17A; ATP6V1B2; HLA-DQA1; IL6; HLA-DRB1; ATP6V1B1|
|Allograft rejection||Il2; HLA-DQA1; CD28; HLA-B; H2-AA; HLA-DRB3; FASLG; HLA-DRA; H2-Q10; HLA-DPA1|
|Graft-versus-host disease||CD86; IL1B; KLRD1; HLA-DMB; FASLG; GZMB; HLA-DRB3; HLA-C; HLA-DQB1; HLA-A|
|Viral myocarditis||SGCG; HLA-DMB; HLA-DPA1; CAV1; HLA-DMA; ITGAL; Casp3; HLA-DRB5; HLA-B; SGCD|
cd80 has several biochemical functions, for example, coreceptor activity, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cd80 itself. We selected most functions cd80 had, and list some proteins which have the same functions with cd80. You can find most of the proteins on our site.
|coreceptor activity||ZP2; CXCR4; LY96; CXCR7; CCR8; CXCR6; RGMA; CD4; CD8B; ACKR3B|
|protein binding||NKD1; JAGN1; ANXA9; RNF40; DNTT; PAX9; FAM125B; RBP5; PSMA7; MPP5|
|virus receptor activity||HTR2A; CLDN1; CD209; ACE2; PVRL4; SLAMF1; CXADR; PVRL1; HSPA1A; ICAM1|
cd80 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd80 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd80.
CTLA4; NGFR; CD28; CD86; CD274