Recombinant Human CD83 protein, hFc-tagged

Cat.No. : CD83-7854H
Product Overview : Recombinant Human CD83 protein(Q01151-1)(Thr20-Ala143), fused with C-terminal hFc tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : C-hFc
Protein length : Thr20-Ala143
Form : Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Bio-activity : Immobilized Human CD83, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD83 Antibody, hFc Tag with the EC50 36.9ng/ml determined by ELISA (QC Test).
Molecular Mass : The protein has a predicted MW of 40.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
Endotoxin : Less than 1EU per μg by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Storage : Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD83 CD83 molecule [ Homo sapiens ]
Official Symbol : CD83
Synonyms : CD83; CD83 molecule; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) , CD83 molecule; CD83 antigen; BL11; HB15; hCD83; B-cell activation protein; cell surface protein HB15; cell-surface glycoprotein; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily);
Gene ID : 9308
mRNA Refseq : NM_001040280
Protein Refseq : NP_001035370
MIM : 604534
UniProt ID : Q01151

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
03/16/2021

    The experimental conditions are wide, and the experimental results are accurate and reproducible.

    08/24/2020

      The resulting strips are clear and bright, which greatly exceeds the expected results.

      06/10/2020

        CD83 activity is maintained for a very long time and can be maintained for a long time, which is very stable and reliable.

        Q&As (6)

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        Could CD83 be a target for immunotherapy? 12/19/2021

        Yes, CD83 can be targeted as immunotherapy. Immunotherapy for CD83 has been explored in several clinical trials with some efficacy.

        Are there population differences in CD83 treatment? 10/27/2021

        It is unclear whether there is a population difference in CD83 treatment. However, due to factors such as individual differences and genetic polymorphisms, different populations may respond differently to treatment. Therefore, population-specific treatment strategies may need to be individually adapted and optimized.

        What are possible aspects of future research on CD83? 09/02/2021

        Future research on CD83 may involve more in-depth molecular mechanism studies, optimization and improvement of CD83-based immunotherapy strategies, and research on combination with other immunotherapies or drugs.

        Is there a relationship between CD83 and other immune checkpoint molecules? 03/01/2021

        CD83 interacts and regulates with other immune checkpoint molecules. Together, they are involved in the regulation of the immune response.

        Is CD83 expression regulated by other molecules? 12/20/2020

        Yes, CD83 expression is regulated by a variety of molecules, including cytokines, transcription factors, and epigenetic modifications.

        What is the therapeutic approach for CD83? 08/05/2020

        Current treatments for CD83 mainly include immunotherapy and gene therapy. Immunotherapy against CD83 works primarily by modulating the function of dendritic cells and T cells.

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