Recombinant Human CD83 protein, hFc-tagged
Cat.No. : | CD83-7854H |
Product Overview : | Recombinant Human CD83 protein(Q01151-1)(Thr20-Ala143), fused with C-terminal hFc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-hFc |
Protein length : | Thr20-Ala143 |
Form : | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
Bio-activity : | Immobilized Human CD83, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD83 Antibody, hFc Tag with the EC50 36.9ng/ml determined by ELISA (QC Test). |
Molecular Mass : | The protein has a predicted MW of 40.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Storage : | Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | CD83 CD83 molecule [ Homo sapiens ] |
Official Symbol : | CD83 |
Synonyms : | CD83; CD83 molecule; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) , CD83 molecule; CD83 antigen; BL11; HB15; hCD83; B-cell activation protein; cell surface protein HB15; cell-surface glycoprotein; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); |
Gene ID : | 9308 |
mRNA Refseq : | NM_001040280 |
Protein Refseq : | NP_001035370 |
MIM : | 604534 |
UniProt ID : | Q01151 |
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CD83-751R | Recombinant Cynomolgus/Rhesus CD83 protein(Met1-Ala143), His-tagged | +Inquiry |
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◆ Lysates | ||
CD83-1130CCL | Recombinant Cynomolgus CD83 cell lysate | +Inquiry |
CD83-1432RCL | Recombinant Rat CD83 cell lysate | +Inquiry |
CD83-2095HCL | Recombinant Human CD83 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe experimental conditions are wide, and the experimental results are accurate and reproducible.
The resulting strips are clear and bright, which greatly exceeds the expected results.
CD83 activity is maintained for a very long time and can be maintained for a long time, which is very stable and reliable.
Q&As (6)
Ask a questionYes, CD83 can be targeted as immunotherapy. Immunotherapy for CD83 has been explored in several clinical trials with some efficacy.
It is unclear whether there is a population difference in CD83 treatment. However, due to factors such as individual differences and genetic polymorphisms, different populations may respond differently to treatment. Therefore, population-specific treatment strategies may need to be individually adapted and optimized.
Future research on CD83 may involve more in-depth molecular mechanism studies, optimization and improvement of CD83-based immunotherapy strategies, and research on combination with other immunotherapies or drugs.
CD83 interacts and regulates with other immune checkpoint molecules. Together, they are involved in the regulation of the immune response.
Yes, CD83 expression is regulated by a variety of molecules, including cytokines, transcription factors, and epigenetic modifications.
Current treatments for CD83 mainly include immunotherapy and gene therapy. Immunotherapy against CD83 works primarily by modulating the function of dendritic cells and T cells.
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