Recombinant Human CD86 Protein, His-tagged, Alexa Fluor 647 conjugated

Cat.No. : CD86-2228HAF647
Product Overview : Alexa Fluor 647 conjugated recombinant human CD86 extracellular domain (Met 1-His 239) (NP_008820.2), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.
Availability July 19, 2024
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized
Molecular Mass : The recombinant human B7-2 consists of 228 amino acids and has a predicted molecular mass of 26.2 kDa. In SDS-PAGE, the apparent molecular mass of rhB7-2 is approximately 55-60 kDa due to glycosylation.
Protein length : 228
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 647 via amines
Excitation = 650 nm
Emission = 668 nm
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : CD86 CD86 molecule [ Homo sapiens ]
Official Symbol : CD86
Gene ID : 942
mRNA Refseq : NM_001206924
Protein Refseq : NP_001193853
MIM : 601020
UniProt ID : P42081

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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01/09/2022

    With the CD86 protein's high-quality composition and reliability, researchers can confidently proceed with their studies, knowing that they have access to a protein that consistently delivers accurate results.

    05/30/2021

      Its high purity and stability ensure reliable and reproducible results, which are paramount for achieving meaningful scientific outcomes.

      12/08/2017

        The CD86 protein is renowned for its outstanding quality, making it an optimal choice to fulfill the requirements of my experimental investigations.

        Q&As (5)

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        Are there any ongoing clinical trials involving CD86 inhibitors? 02/18/2023

        Yes, several clinical trials are investigating the efficacy of CD86 inhibitors in various diseases, including autoimmune disorders and certain cancers.

        How does CD86 contribute to transplant medicine? 02/03/2021

        In transplantation, CD86 blockade is investigated as a potential strategy to modulate the immune response and prevent graft rejection by inhibiting excessive T cell activation.

        How does CD86 influence the balance between Th1 and Th2 immune responses? 08/26/2019

        CD86 signaling is involved in the differentiation of T helper cells. Modulating CD86 levels may influence the balance between Th1 and Th2 responses, which is relevant in various immune-mediated diseases.

        Can CD86 be used as a prognostic marker in certain diseases? 12/29/2018

        There is emerging evidence suggesting that CD86 expression levels may have prognostic value in certain diseases, guiding clinicians in predicting disease outcomes.

        How does CD86 influence the development of regulatory T cells (Tregs)? 10/02/2016

        CD86 signaling is involved in the development and function of regulatory T cells, which play a crucial role in maintaining immune tolerance and preventing autoimmune reactions.

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