Description : |
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
92.3 kDa |
AA Sequence : |
MPRIMIKGGVWRNTEDEILKAAVMK YGKNQWSRIASLLHRKSAKQCKARW YEWLDPSIKKTEWSREEEEKLLHLA KLMPTQWRTIAPIIGRTAAQCLEHY EFLLDKAAQRDNEEETTDDPRKLKP GEIDPNPETKPARPDPIDMDEDELE MLSEARARLANTQGKKAKRKAREKQ LEEARRLAALQKRRELRAAGIEIQK KRKRKRGVDYNAEIPFEKKPALGFY DTSEENYQALDADFRKLRQQDLDGE LRSEKEGRDRKKDKQHLKRKKESDL PSAILQTSGVSEFTKKRSKLVLPAP QISDAELQEVVKVGQASEIARQTAE ESGITNSASSTLLSEYNVTNNSVAL RTPRTPASQDRILQEAQNLMALTNV DTPLKGGLNTPLHESDFSGVTPQRQ VVQTPNTVLSTPFRTPSNGAEGLTP RSGTTPKPVINSTPGRTPLRDKLNI NPEDGMADYSDPSYVKQMERESREH LRLGLLGLPAPKNDFEIVLPENAEK ELEEREIDDTYIEDAADVDARKQAI RDAERVKEMKRMHKAVQKDLPRPSE VNETILRPLNVEPPLTDLQKSEELI KKEMITMLHYDLLHHPYEPSGNKKG KTVGFGTNNSEHITYLEHNPYEKFS KEELKKAQDVLVQEMEVVKQGMSHG ELSSEAYNQVWEECYSQVLYLPGQS RYTRANLASKKDRIESLEKRLEINR GHMTTEAKRAAKMEKKMKILLGGYQ SRAMGLMKQLNDLWDQIEQAHLELR TFEELKKHEDSAIPRRLECLKEDVQ RQQEREKELQHRYADLLLEKETLKS KFTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |